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Table 3 DLA STR-based class I and II haplotypes and their frequencies in standard poodles (n = 673), Miniature Poodles (n = 16), and miniature/standard poodle crosses (72)

From: The effect of genetic bottlenecks and inbreeding on the incidence of two major autoimmune diseases in standard poodles, sebaceous adenitis and Addison’s disease

Class I    Class II    
ID Haplotype Frequency ID Haplotype Frequency DLA-DRB1/DQA1/DQB1
1001 380/373/281/182 0.259 2001 343/324/284 0.605 01501/00601/02301
1002 380/365/281/181 0.200 2002 343/327/280 0.091 01501/00901/00101
1003 387/375/277/186 0.157 2003 343/324/282 0.092 01503/00601/02301
1004 393/379/277/183 0.090 2004 351/327/268 0.027 02001/00401/01303
1005 389/371/277/181 0.056 2005b 339/322/280 0.024 00101/00101/00201
       00901/00101/008011
1006 387/375/293/180 0.043 2006 339/325/280 0.032 01502/00601/02301
1007 380/372/281/182 0.031 2007 351/327/280 0.016 02001/00401/01303
1008 386/373/289/182 0.018 2008 339/327/276 0.011 00101/00101/03601
1009 382/377/277/184 0.011 2009 351/324/280 0.016  
1010 384/371/277/186 0.016 2010 345/329/280 0.016 01201/00401/013017
1011 376/365/281/180 0.020 2011c 345/322/284 0.020 00901/00101/008011
1012 388/369/289/188 0.011 2012c 345/322/280 0.008 00901/00101/008011
1013 392/373/289/186 0.010 2013 345/327/284 0.008 00201/00901/00101
1014 375/373/287/178 0.008 2014 339/322/284 0.005  
1015 380/373/291/186 0.003 2015a 339/327/280 0.005  
1016 382/371/277/178 0.005 2016c 339/323/284 0.003 00601/05011/00701
1017 386/373/289/178 0.005 2017 343/322/280 0.004  
1018a 375/373/287/186 0.013 2018c 339/324/284 0.001 00601/05011/00701
1019 380/373/287/185 0.003 2019 345/324/284 0.001  
1020a 388/369/289/184 0.004 2020 349/324/284 0.001  
1021 380/373/289/186 0.003 2021a 339/324/268 0.001  
1022 380/375/281/181 0.001 2022 339/327/282 0.001  
1023 380/379/281/181 0.001 2023 341/323/282 0.006  
1024 387/373/281/182 0.001 2024a 343/323/280 0.001  
1026 390/369/289/186 0.001 2025a 351/321/280 0.002  
1027 391/371/277/181 0.001 2026 351/324/284 0.001  
1028a 376/369/291/186 0.001 2027 343/325/284 0.001  
1029 380/365/281/182 0.003 2028a 345/327/288 0.001  
1030 380/373/293/178 0.006     
1031a 382/371/277/186 0.003     
1032a 382/377/277/178 0.001     
1033a 382/379/277/181 0.001     
1034a 382/379/277/182 0.001     
1035 386/373/277/184 0.001     
1036a 389/365/289/180 0.002     
1039 379/364/281/181 0.001     
1040a 380/371/277/186 0.001     
1041 386/374/277/186 0.001     
1042 389/375/293/186 0.001     
1043 393/381/277/183 0.001     
1045 376/371/277/186 0.001     
1046 376/379/291/180 0.001     
1057 387/376/277/186 0.001     
  1. aAssociated with Miniature Poodles
  2. bSingle STR haplotype associated with two known exon 2 sequence based haplotypes
  3. cTwo different STR haplotypes associated with the same exon 2 sequence based haplotype
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Canine Medicine and Genetics

ISSN: 2662-9380